Lauroyl-L-aspartate decreased food intake and body temperature in neonatal chicks

Edi Erwan, and V.S. Chowdhury, and K.Ito, and Mitsuhiro Furuse, (2013) Lauroyl-L-aspartate decreased food intake and body temperature in neonatal chicks. Pharmacology, Biochemistry and Behavior. pp. 7-11.

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Abstract

We hypothesized that the effects of L- andD-amino acids might be influenced when conjugated with fatty acid. Thus, the effects of oral administration of lauroyl-L-aspartate (Lau-L-Asp) as well as lauroyl-D-aspartate (Lau-D-Asp) were examined. In Experiment 1, oral administration of both Lau-L-Asp and Lau-D-Asp decreased food intake while L- or D-Asp did not influence food intake. Interestingly, only Lau-L-Asp decreased body temperature. Experiment 2 was conducted to determine whether non-conjugated mixture of L-Asp plus lauric acid has same effects under ad libitum feeding conditions. Lau-L-Asp decreased food intake and body temperature, but L-Asp plus lauric acid did not show any effect studied. In Experiment 3, we found that Lau-L-Asp declined food intake as well as time-dependently suppressed the body temperature in fasted chicks. However, L-Asp plus lauric acid did not show any effect. These results suggest that Lau-L-Asp may exert anorexigenic and hypothermic actions in chicks.

Item Type: Article
Subjects: 600 Teknologi dan Ilmu-ilmu Terapan > 630 Usaha Tani, Pertanian, Teknologi Pertanian > 630.7 Pendidikan Pertanian, Riset Penelitian Pertanian
Divisions: Fakultas Pertanian dan Peternakan > Agroteknologi
Depositing User: Ari Eka Wahyudi
Date Deposited: 15 Apr 2019 04:28
Last Modified: 15 Apr 2019 04:28
URI: http://repository.uin-suska.ac.id/id/eprint/12755

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